Sec.2-Ch.1-Subsec.4：Detecting Publication Bias in Binary Outcome Meta-Analysis with R

Funnel Plots, Trim-and-Fill Correction, and Contour-Enhanced Funnel Plot Interpretation Using the Fleiss93 Dataset

I. Review of Previous Content: Formula Construction and Result Interpretation

The Fleiss93 dataset comes from the meta extension package and includes seven clinical trials conducted in the 1970s–1980s on aspirin for the prevention of mortality after myocardial infarction.

Sec.2-Ch.1-Subsec.3：Fixed-Effect Dose–Response Modeling in R

This article is based on the Fleiss93 dataset and uses the meta extension package to conduct a meta-analysis of binary outcomes, with a detailed discussion of the relevant statistical methods and interpretation of heterogeneity and effect sizes.

library(meta)
data(Fleiss93)
str(Fleiss93)
head(Fleiss93)