Exploring Medical Data Science with R

Exploring Medical Data Science with R

Meta & Bibmetrics

Sec.2-Ch.1-Subsec.6:Meta-Analysis of Continuous Variables in R

From Theory to Practice with Visualization and Sensitivity Analysis

Dr. Xie YJ's avatar
Dr. Xie YJ
Feb 06, 2026
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Meta-analysis is a method for synthesizing results from multiple studies and is commonly used to evaluate the overall effect of an intervention or treatment. In many scientific studies, meta-analysis helps assess the robustness and generalizability of experimental data. Especially in the fields of medicine and psychology, meta-analysis can effectively integrate heterogeneity across studies, improving statistical power and the accuracy of results.

This article focuses on meta-analysis of continuous variables, particularly using the meta extension package in R. The analysis is demonstrated using the Fleiss93cont dataset.


I. The Fleiss93cont Dataset

The Fleiss93cont dataset in the R meta extension package originates from a meta-analysis published by E. Mumford et al. (1984) on the impact of mental health treatment on medical service utilization. The dataset contains basic information from five studies, including study year, sample sizes, means, and standard deviations for both treatment and control groups.

library(meta)
data(Fleiss93cont)
Fleiss93cont

The contents of the Fleiss93cont dataset are as follows:

    study   year n.e mean.e sd.e n.c mean.c sd.c
1   Davis  1973  13    5.0  4.70  13   6.50  3.80
2 Florell  1971  30    4.9  1.71  50   6.10  2.30
3   Gruen  1975  35   22.5  3.44  35  24.90 10.65
4    Hart  1975  20   12.5  1.47  20  12.30  1.66
5  Wilson  1977   8    6.5  0.76   8   7.38  1.41
  • study: study label

  • year: year of the study

  • n.e: total number of participants in the treatment group

  • mean.e: mean outcome in the treatment group

  • sd.e: standard deviation in the treatment group

  • n.c: total number of participants in the control group

  • mean.c: mean outcome in the control group

  • sd.c: standard deviation in the control group

The dataset contains 5 studies, primarily used to analyze the impact of mental health treatment on medical service utilization.

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